shifting
the horizon
to make better medicines

We are The Machine Learning Immunology Company

Seismic Therapeutic™ is a clinical-stage, product-centric immunology company powered by proprietary machine learning technology. We are creating transformative biologic medicines for autoimmune and inflammatory diseases.

Patient Impact Drives our Innovation

We are advancing a deep pipeline of first-in-class and best-in-class programs targeting the adaptive immune system:

Cell-Mediated Immune Diseases
Multi-functional antibodies for T cell-driven autoimmune diseases are designed to engage multiple inhibitory pathways across cell types and regulate both sides of the immune synapse for superior efficacy.
Allergic Diseases
IgE-targeted approaches for allergic diseases are engineered to disarm mast cells and basophils, and shut down IgE-mediated inflammation at its source.
Antibody-Mediated Immune Diseases
Immunoglobulin Sculpting (IgSc) enzymes for antibody-mediated immunologic diseases built to eliminate pathogenic immunoglobulins, including via IgG proteases, while preserving immune balance.

Pipeline

Integration is at Our Epicenter

Our IMPACT platform integrates structural biology with machine learning to design novel biologics. Parallel optimization of multiple molecular attributes accelerates our path from concept to clinic.

Platform

Hyper-Collaboration Fuels Our Focus

Seismic brings together leaders in antibody engineering, immunology, machine learning, and clinical development—backed by top-tier life science investors. Our team combines deep expertise in immune-cell biology with a track record of advancing breakthrough therapies to patients with autoimmune disease. We believe our impact on drug discovery is inseparable from our commitment to collaboration across disciplines.

AboutCulture

Recent Shifts & Advances

See what’s happening at Seismic Therapeutic™ with our latest news and events.

January 6, 2026
Seismic Therapeutic Announces Updated Presentation Time at the 44th Annual J.P. Morgan Healthcare Conference Read more
October 27, 2025
ACR Posters Read more
October 21, 2025
Seismic Therapeutic Announces Publication Demonstrating Activity of Immunoglobulin Proteases in Autoantibody-Driven Diseases Read more
 

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