At Seismic, our open and hyper-collaborative process is what yields results. We gain focus alongside curiosity. We are dedicated to our rigorous science and determined to have impact for patients. Doing it all, together, is what keeps us going. Let’s fuse our ideas and open the door to the uncharted.

Inspired
to do more.
Being a Seismonaut means being relentlessly curious, open, transparent, and decisive. But above all, putting the team first. Here’s how we do it:
Intensive
At Our Core
We have our eyes on the prize - combining a level of accountability with exceptional, exciting science, but we also have a serious respect for our goals and believe in our people.
Inclusive
In Our Approach
We are open to the possibilities of the new and the uncharted. We fully believe that our impact on the drug discovery paradigm directly correlates to our willingness to embrace curiosity.
Integrative
In Our Process
We believe our hyper-collaborative style provides a fertile ground for discovery, having a positive impact both inside and outside of Seismic.

While we are focused on this new era of drug discovery, our main focus is our why: creating IMPACT for patients.

We need you on our team.

Get Inspired at Seismic.

Senior Vice President, Finance

About Seismic

Seismic Therapeutic is a biotechnology company integrating machine learning to accelerate immunology drug development. Using its IMPACT™ platform, the company is addressing the central challenges of biologics discovery and development by fully integrating machine learning with structural biology, protein engineering and translational immunology to create optimized therapies for patients with autoimmune disease. The company has raised $222M to date from a strong syndicate of life sciences investors (Lightspeed Venture Partners, Bessemer Venture Partners, Tim Springer, Polaris, GV, Boxer, Samsara, Amgen Ventures and others) and is located in the Boston-Watertown biotechnology hub.

The Opportunity

Seismic is seeking an experienced Finance/Accounting professional to serve as SVP, Finance to build, lead and run Seismic’s Finance and Accounting organization. This is an exciting opportunity to join as a key member of the Seismic Leadership Team.

The SVP, Finance will have a vision for Seismic’s Finance function and needs; will establish key systems and best practices, and be the overall responsible day-to-day leader of Finance from a strategic, technical, and operational standpoint.

In addition to being a key contributor to corporate strategy, this is a role that requires a dynamic, hands-on leader, who will move proactively to lead the accounting, FP&A, and financial reporting functions.

The Role

This position requires a strategically minded, accomplished, and motivated finance/accounting professional with a track record of delivering consistent results in dynamic, high-growth businesses.

The SVP, Finance will be responsible and accountable for:

Strategic Vision and Engagement

  • Working with the Consulting CFO and CEO to develop an overall vision for Seismic’s Finance function to fit the needs of the company.
  • Growing, leading, motivating, developing, and coaching a best-in-class accounting function that is viewed as a business partner and expert on accounting, controls and reporting matters while providing guidance and assistance to other departments as needed.
  • Contribute important accounting, tax, reporting insights as well as relevant financial analysis to important strategic decisions.

Advanced Finance Acumen

  • Build, manage and maintain the company’s system of internal financial controls.
  • Manage the timely and accurate preparation of monthly financial statements and related reports for internal distribution as well the preparation of quarterly and annual financial statements.
  • Manage the planning and successful execution of quarterly reviews and annual audits conducted by the Company’s external audit firm.
  • Work closely with the Consulting CFO and CEO on treasury activities including cash and investment management matters.
  • Manage currently outsourced functions such as income taxes and procurement activities, including evaluation of the current process and structure and recommending and implementing changes in either, as needed.
  • Ensure that all federal, state and local tax returns and filings are completed accurately and on a timely basis.
  • Participate in senior leadership meetings preparing and presenting relevant documents, reports and plans in a timely manner.
  • Evaluate existing accounting processes and technologies, implementing changes for improvement and manage implementation of new processes and technologies as identified.
  • Interface with the Audit Committee of the Board, ensuring they have a clear sense of the overall financial health and potential risk areas of the company.
  • Identify and lead financial systems migration/implementation, partner with all internal stakeholders, and manage external relationships with auditors, insurance and other vendors as required.
  • Maintain prudent risk policies and exposures.

FP&A Accountability

  • Manage and maintain the Company’s strategic finance capability (FP&A); establish and maintain a culture of financial forward-thinking, and financial analysis to underpin the Company’s strategy, decisions, and planning.
  • Co-lead the Company’s strategic resource planning, budget and allocation process (LRP) with other key stakeholders.
  • Maintain accounting practices under US GAAP and SEC requirements and manage internal controls.
  • Preparation of annual budgets and periodic forecasts.

 

Your Background:

  • Bachelor’s degree in Accounting. CPA/MBA is strongly preferred.
  • Minimum of 15+ years of progressively increasing responsibilities in accounting and financial roles, including minimum of 3 years at a Big 4 Accounting firm and ideally 3- 5 years of Controllership and FP&A experience. Public company experience required, and biotech/pharmaceutical industry experience strongly preferred.
  • Minimum of 5 years of leadership experience building, developing and leading a high performing team in a high growth organization. Strong leadership ability to guide and coach a team in day-to-day and long-term related activities.
  • Broad overall business perspective especially about issues facing biotech and drug development companies that will allow the person to identify trends, anticipate and recognize early signs of challenges, problems or opportunities, and communicate solutions or recommendations to address them.
  • Excellent accounting and analytical skills and ability to identify potential accounting or reporting issues that may arise from future strategic transactions and the ability to offer insights into how they may be avoided or mitigated. Ability to assess the impact of pending or future planned accounting or tax rules on Seismic Therapeutic.
  • Self-starter with the ability to set priorities for themselves and for the team in order to meet specific deadlines in a fast paced and entrepreneurial environment. Ability to be flexible, accommodating and deal with change effectively. Ability to manage projects with participants and audience ranging from entry-level to Board-level.
  • Ability and willingness to dive deep into details when needed, and exert extra effort when required, while at the same time maintaining clear view of the strategic “big picture” and priorities.
  • Strong ability to build good working relationships with cross-functional business teams. Work effectively in and contribute to a team environment. Approaches work with a positive, team-first attitude.
  • Outstanding written and verbal communication, including running meetings and preparing presentations for internal and external groups. Ability to communicate effectively with team and Senior Management.
  • Someone who will embrace Seismic’s culture, values and exhibits a high degree of integrity and ethics, and shares Seismic’s commitment to an inclusive and supportive culture.

This position will be in our Watertown, MA office location.

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion and talent – we’ll bring novel therapeutics to the patients who need them the most.

APPLY HERE

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran’s status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.

 

Principal/Senior Scientist Protein Analytics

Are you looking for a new challenge in a dynamic, fast-paced startup environment? Seismic Therapeutic, a biotechnology startup focused on the intersection of structure, protein engineering, machine learning, and immunology, is seeking an experienced and motivated principal scientist to help drive novel immunotherapy programs.

At Seismic, we’re determined to help patients with unmet need by integrating cutting-edge technology and innovative science to generate clinic-ready drugs. We’re looking for a rigorous scientist with extensive experience in antibody/protein analytics to join our superstar team.

As a principal scientist, you will design, optimize, and manage protein expression and purification workflows of various antibody formats. You’ll spend roughly 70% of your time on lab-based activities, characterizing antibodies to assess biochemical/biophysical properties. You’ll also have the opportunity to manage and mentor research associates, co-lead programs, and collaborate with diverse teams of scientists.

We’re looking for someone who is intellectually curious with a passion for exploring new approaches to accelerate the pace of research without compromising quality. Someone who is enthusiastic, innovative, and bold in proposing creative experimental designs and ideas, and who is relentless in pursuing successful outcomes. Someone who is driven and conscientious, thriving in a fast-paced, entrepreneurial environment, and who is passionate about improving patients’ lives.

Qualifications:

  • PhD with 7+ years’ experience in chemistry, biology, biochemistry, biomedical engineering, or related field
  • Expertise in protein purification and analytics
  • Experience directing Research Associates, Technicians, and CRO’s
  • This is an on-site, lab-based role

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion, and talent, we’ll bring novel therapeutics to the patients who need them the most. Join us and help us change the world!

APPLY HERE

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran’s status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.

 

Scientist, Biotherapeutics

Seismic Therapeutic, a biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology, is seeking an exceptional and enthusiastic Scientist to help drive novel immunotherapy programs. The successful candidate will contribute to Seismic’s mission to develop novel immunotherapies and create an IMPACT on diseases of the adaptive immune system by expressing, purifying, and characterizing therapeutic molecules.

About Seismic: Seismic is determined to help patients with unmet need by integrating machine learning, structural biology, protein engineering, and translational immunology to generate clinic-ready drugs. At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that.

Who You Are: 

  • A rigorous scientist with a background in biochemistry and protein analytics.
  • A person with a keen eye for detail, exceptional time management skills and an organized approach.
  • A team-player who thrives in a scientifically diverse, fast-paced, collaborative start-up environment.
  • Eager to contribute to shaping an open, inclusive, and rigorous company culture by embracing teamwork, creativity, and a can-do attitude; lead by example to create and sustain an intellectually rich and dynamic work environment that is supportive and inclusive.
  • Passionate about improving patients’ lives.

Responsibilities:

  • Express and purify therapeutic molecules across multiple scales in various systems.
  • Characterize molecules using a variety of analytical techniques to assess purity, stability, and other biochemical and biophysical properties.
  • Develop and execute high-throughput assays to assess the feasibility of early therapeutic candidates.
  • Collaborate and communicate in a matrixed environment.
  • Detailed documentation, analysis, and interpretation of experiments.

Required Qualifications:

  • PhD in biochemistry/biophysics, biological/chemical engineering, or a related discipline with 0-2 years experience
  • Experience in protein expression, purification using a variety of techniques (affinity, SEC, IEX, mixed-mode, etc.), and analytical characterization.
  • Experience in diverse biochemical and biophysical techniques such as DSF, DLS, IEF is a plus.
  • Experience working with bispecific and non-traditional antibody formats is a plus.

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion and talent – we’ll bring novel therapeutics to the patients who need them the most.

APPLY HERE

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran’s status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.

Associate Director/Director, Program Management

Seismic Therapeutic, a biotechnology startup focused on the intersection of structural biology, protein engineering, machine learning and immunology, is seeking an experienced and motivated Associate Director / Director of Program Management to work closely with the program lead(s), cross-functional program teams and senior scientific team to develop and execute the strategy and operations for one or more of our research and early development programs.

About Seismic:

Seismic is determined to help patients with unmet need by integrating machine learning, structural biology, protein engineering, and translational immunology to generate clinic-ready drugs. At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that.

Who You Are:

  • A dynamic program manager with deep knowledge of the drug discovery and development process, including demonstrated experience with leading programs through preclinical development and regulatory submission, with a strong preference for early clinical development experience with biologics development and product candidates in immunology
  • An effective communicator with ability to create materials and present complex scientific and strategic topics to variety of audiences, including senior leadership
  • Able to lead through influence and strong collaborative skills
  • Exceptional organizational skills, with ability to manage multiple cross-functional projects
  • Strong interpersonal skills to motivate others, reach organizational alignment and manage conflict, including collaborating with scientists at all levels
  • Proactive and “roll-up your sleeves” to dive in with minimal supervision and thrive in a fast-paced, fluid environment
  • Passionate about improving patients’ lives

What You’ll Do:

  • Partner with the program lead(s) to manage one or more cross-functional program team(s) to ensure achieving key program and corporate objectives
  • Accountable for developing and maintaining cross-functional program timelines and tracking progress
  • Collaborate with team members to develop integrated product plan outlining product strategies, functional strategies and interdependencies
  • Proactively identify and facilitate decision making including scenario planning, decision criteria, articulating tradeoffs and implications on timelines, resources and objectives
  • Maintain program workbook to track project goals, milestones and action, risks and decision logs and ensure clear and timely communication to teams and senior leadership
  • Plan and facilitate program team meetings to ensure robust scientific discussions, operational coordination, and strategic planning
  • Enable effective and consistent performance within program teams including supporting and coaching team members to optimize collaboration and delivery
  • Partner with program management colleagues to ensure consistency, and coordination across portfolio, and establish/evolve best practices and help instill project management into our teams as our pipeline grows and matures

Qualifications:

  • BS in scientific field required; MS in life sciences or MBA preferred
  • 6-10 years of experience in a biotechnology or pharmaceutical setting and at least 5 years in program management with a demonstrated competency with programs in clinical stage, in particular for biologics in immunologic diseases
  • Strong analytical and technical skills, including proficiency in project management practices, project planning, and decision-making.
  • Command of MS office suite and project management tools (MS Project/Timeline, ThinkCell)
  • Experience in both large and small company environments a plus.

This position will be in our Watertown, MA office location.

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion and talent – we’ll bring novel therapeutics to the patients who need them the most.

APPLY HERE

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran’s status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.

 

Associate Scientist/Senior Associate Scientist-Protein Analytics

Seismic Therapeutic, a biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology, is seeking an experienced and motivated Associate Scientist to help drive novel immunotherapy programs. The successful candidate will play a significant part on our drug discovery and development efforts by expressing, purifying, and characterizing therapeutic molecules.

About Seismic: Seismic is determined to help patients with unmet need by integrating machine learning, structural biology, protein engineering, and translational immunology to generate clinic-ready drugs. At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that.

Who You Are: 

  • A meticulous scientist with biochemistry and protein analytics work experience.
  • Organized with a strong attention to detail and good time management.
  • A collaborative teammate who thrives in a scientifically diverse, fast-paced, team-oriented, start-up environment.
  • Eager to contribute to shaping an open, inclusive, and rigorous company culture.
  • Someone who shares our passion for making a difference in patients’ lives.

Responsibilities:

  • Express and purify therapeutic molecules across multiple scales from bacterial and mammalian systems.
  • Support analysis of proteins to determine biochemical and biophysical characteristics such as purity, homogeneity, size, and stability.
  • Engage and collaborate with cross functional teams to effectively investigate therapeutic candidate molecules
  • Carefully document research and effectively communicate results to relevant members of the team.

Qualifications:

  • Bachelor’s or Master’s Degree in biochemistry/biophysics, biological/chemical engineering or a related discipline with 2+ years of experience in a biotech/pharmaceutical industry setting.
  • Experience with protein expression, purification, and characterization using analytical methods such as SDS-PAGE, Western blot, HPLC, and ELISA.
  • Experience in biochemical and biophysical techniques such as SPR, BLI, DSF, or DLS is a plus.
  • Experience with multispecific antibodies, fusion proteins, and other non-traditional antibody formats is a plus.

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion and talent – we’ll bring novel therapeutics to the patients who need them the most.

 

APPLY HERE

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran’s status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.

A Space for Seismic Discovery

Shifting the horizon requires creating the right environment for our Seismonauts to thrive. Our space fosters the inclusivity and integration we run on – with open collaborative work areas that allow cross- pollination of interests and departments. However, setting the stage for success goes beyond our galaxy walls. Seismic offers a competitive benefits package that is structured to create balance and maintain the expertise and talent we need on our mission.

Be an IMPACTor

Our team of Seismonauts is passionate about shifting things for the better, not only in developing breakthrough medicines, but also in making a difference to the causes and communities that matter to us.

Our IMPACTor Leaders show us the way. As an employee-led collaborative, IMPACTors initiate social events, elevate diversity awareness, and host philanthropic and volunteer activities. These initiatives are proudly started within Seismic, but have profound impact in the community.

 
 

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